ZFIN ID: ZDB-GENE-050803-1
Gene Name: ezrin b
Gene Symbol: ezrb    Nomenclature History

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Previous Names: ezr, cb567 (1), ezrin2 (1), vil2 (1), wu:fc05c03 (1), wu:fj31d06 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have actin binding activity. Involved in several processes, including cell migration involved in gastrulation; epiboly; and regulation of cilium assembly. Predicted to localize to cytoskeleton. Is expressed in several structures, including anterior axial hypoblast; digestive system; hatching gland; nervous system; and prechordal plate. Orthologous to human EZR (ezrin).
Genome Resources: Alliance (1),  Gene:561589 (1),  Ensembl(GRCz11):ENSDARG00000025091 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6621 Point Mutation Unknown Premature Stop ENU
sa14485 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14899 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23649 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36988 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ezrb N/A 5
    MO2-ezrb N/A 7
    DISEASE ASSOCIATED WITH ezrb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ezrb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ezrb-202 (1)    Ensembl 2812
    ezrb-203 (1)    Ensembl 608
    ezrb-204 (1)    Ensembl 182
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-ezrb polyclonal Rabbit IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ezrb No data available
    MARKER RELATIONSHIPS
    ezrb Contained in: [BAC] CH211-122H15
    ezrb Encodes: [EST] cb567 (1) (order this), fc05c03, fj31d06, IMAGE:7140274 (1)
    [cDNA] MGC:161977 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030285 (1) 2720 nt
    Genomic GenBank:BX248246 (1) 176239 nt
    Select Tool
    Polypeptide UniProtKB:Q5TZG5 (1) 583 aa
    Sequence Information (all 21)
    ORTHOLOGY for ezrb ( Chr: 20 )
    CITATIONS (32)