Gene

mlc1

ID
ZDB-GENE-050419-145
Name
modulator of VRAC current 1
Symbol
mlc1 Nomenclature History
Previous Names
  • si:ch211-192n14.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Involved in protein localization to cell surface. Localizes to cell-cell junction. Is expressed in nervous system and radial glial cell. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts 1. Orthologous to human MLC1 (modulator of VRAC current 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mlc1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
megalencephalic leukoencephalopathy with subcortical cysts 1 Alliance Megalencephalic leukoencephalopathy with subcortical cysts 604004
Associated With mlc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR033280 Membrane protein MLC1
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-mlc1 polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations