ZFIN ID: ZDB-GENE-050320-140
Gene Name: astrotactin 1
Gene Symbol: astn1    Nomenclature History

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Previous Names: zgc:113405, zgc:158703

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to be involved in neuron cell-cell adhesion and neuron migration. Predicted to localize to endosome and integral component of membrane. Used to study schizophrenia. Orthologous to human ASTN1 (astrotactin 1).
Genome Resources: Alliance (1),  Gene:791157 (1),  Ensembl(GRCz11):ENSDARG00000068323 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a235 Indel Unknown Unknown CRISPR
la014921Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023624Tg Transgenic Insertion Unknown Unknown DNA
    sa16944 Point Mutation Unknown Splice Site ENU
    sa19808 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30598 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32958 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38341 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-astn1 1
    CRISPR2-astn1 1
    CRISPR3-astn1 1
    CRISPR4-astn1 1
    DISEASE ASSOCIATED WITH astn1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH astn1 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    schizophrenia astn1a235/a235 standard conditions Thyme et al., 2019
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuron cell-cell adhesion (more)
    Cellular Component integral component of membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA astn1-202 (1)    Ensembl 1288
    astn1-203 (1)    Ensembl 937
    astn1-204 (1)    Ensembl 2344
    Browsers: UCSCEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM astn1 No data available
    MARKER RELATIONSHIPS
    astn1 Contained in: [BAC] CH73-186E16 (1), DKEY-21A8 (1) (order this), DKEYP-81G7 (1)
    astn1 Encodes: [cDNA] MGC:113405 (1), MGC:158703 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013561 (1)
    Genomic GenBank:CT027684 (1) 368196 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q5X4 (1) 1305 aa
    Sequence Information (all 44)
    ORTHOLOGY for astn1 ( Chr: 2 )
    CITATIONS (24)