ZFIN ID: ZDB-GENE-050320-116
Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 3
Gene Symbol: xrcc3
Sequence Ontology ID : SO:0000704

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Previous Names: im:7142103, si:dkey-11b8.1, zgc:101608

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity; predicted to be involved in double-strand break repair via synthesis-dependent  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101608]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10430 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH xrcc3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    breast cancer {Breast cancer, susceptibility to} 114480
    {Melanoma, cutaneous malignant, 6} 613972
    DISEASE ASSOCIATED WITH xrcc3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA repair (more)
    Cellular Component Rad51B-Rad51C-Rad51D-XRCC2 complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013632 (1)
  • InterPro:IPR016467 (1)
  • InterPro:IPR020588 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR033925 (1)
  • PROSITE:PS50162 (1)
  • Pfam:PF08423 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA xrcc3-201 (1) 1672
    xrcc3-202 (1) 777
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM xrcc3 No data available
    MARKER RELATIONSHIPS
    xrcc3Contained in: [BAC] DKEY-11B8 (1) (order this)
    xrcc3Encodes: [EST] IMAGE:7142103 (1) (order this)
    [cDNA] MGC:101608 (1) (order this), MGC:191569 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013541 (1) 1441bp
    Genomic GenBank:BX255905 (1) 118677bp
    Select Tool
    Polypeptide UniProtKB:Q5BL30 (1) 352aa
    Sequence Clusters UniGene:75660 (1)
    Sequence Information (all 16)
    OTHER xrcc3 GENE PAGES
  • Alliance (1)
  • Gene:541414 (1)
  • VEGA:OTTDARG00000004930 (1)
  • ORTHOLOGY for xrcc3 (Chr: 20)
    CITATIONS (18)