header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050208-97
Gene Name: solute carrier family 45 member 2
Gene Symbol: slc45a2
Sequence Ontology ID : SO:0001217

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: oca4, aim1 (1), alb (1), albino (1), B gene, im:7138762

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sucrose:proton symporter activity. Involved in melanocyte differentiation and response to light stimulus. Predicted to localize to the membrane. Used to study cataract. Human  ...
GENE EXPRESSION
All Expression Data: 8 figures from 4 publications
Directly Submitted Expression Data: 5 figures (8 images) from Thisse et al., 2004 [IMAGE:7138762]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b4 Insertion Unknown Unknown SPONTANEOUS
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu1844 Point Mutation Exon 6 Missense
    ihb64 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb65 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb66 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • nk1 Point Mutation Exon 6 Premature Stop
    s1154 Unknown Unknown Unknown ENU
    s3567 Unknown Unknown Unknown ENU
    sa16467 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37277 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • slc45a2_unspecified Unspecified Unknown Unknown
    tf31 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti9 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti225 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tj20e Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm83a Unknown Unknown Unknown G_RAYS
  • European Zebrafish Resource Center (EZRC) (order this)
  • tnr39 Point Mutation Unknown Missense ENU
    tnr52 Small Deletion Exon 6 Premature Stop ENU
    tr282 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • zf67 Unknown Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH slc45a2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    oculocutaneous albinism type IV Albinism, oculocutaneous, type IV 606574
    [Skin/hair/eye pigmentation 5, black/nonblack hair] 227240
    [Skin/hair/eye pigmentation 5, dark/fair skin] 227240
    [Skin/hair/eye pigmentation 5, dark/light eyes] 227240
    DISEASE ASSOCIATED WITH slc45a2 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    cataract slc45a2b4/b4 standard conditions Takamiya et al., 2016
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process developmental pigmentation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function sucrose:proton symporter activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR036259 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc45a2-201 (1) 1745
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc45a2 No data available
    MARKER RELATIONSHIPS
    slc45a2 Contained in: [BAC] CH211-71C16 (1) (order this)
    slc45a2 Encodes: [EST] IMAGE:7138762 (1) (order this), wz10994 (1)
    [cDNA] MGC:172272 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110377 (1)
    Genomic GenBank:CR749169 (1) 180295 bp
    Select Tool
    Polypeptide UniProtKB:A8WG95 (1) 554 aa
    Sequence Clusters UniGene:38928 (1)
    Sequence Information (all 12)
    ORTHOLOGY for slc45a2 ( Chr: 21 )
    CITATIONS (227)