ZFIN ID: ZDB-GENE-050208-100
Gene Name: protein kinase C, alpha, a
Gene Symbol: prkcaa
Sequence Ontology ID : SO:0000704

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Previous Names: prkca, im:7139045 (1), si:dkey-8l19.1 (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein serine/threonine kinase activity; involved in blood coagulation; orthologous to human PRKCA (protein kinase C alpha).
GENE EXPRESSION
All Expression Data: 14 figures from 7 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2004 [IMAGE:7139045]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct7aGt Transgenic Insertion Intron 3 Unknown DNA
la015857Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Williams et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH prkcaa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Pituitary tumor, invasive
    DISEASE ASSOCIATED WITH prkcaa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood coagulation (more)
    Molecular Function ATP binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000008 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR000961 (1)
  • InterPro:IPR002219 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR014375 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR017892 (1)
  • InterPro:IPR020454 (1)
  • InterPro:IPR034663 (1)
  • InterPro:IPR035892 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS00479 (1)
  • PROSITE:PS50004 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50081 (1)
  • PROSITE:PS51285 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF00130 (1)
  • Pfam:PF00168 (1)
  • Pfam:PF00433 (1)
  • EC:2.7.11.13 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA prkca-001 (1) 2172
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM prkcaa No data available
    MARKER RELATIONSHIPS
    prkcaaContained in: [BAC] CH211-152N14 (1) (order this), DKEY-8L19 (1) (order this)
    prkcaaEncodes: [EST] IMAGE:7139045 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001256241 (1) 2172bp
    Genomic RefSeq:NW_018394634 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QIY5 (1) 670aa
    Sequence Clusters UniGene:33991 (1)
    Sequence Information (all 17)
    OTHER prkcaa GENE PAGES
  • Alliance (1)
  • Gene:497384 (1)
  • VEGA:OTTDARG00000027246 (1)
  • ORTHOLOGY for prkcaa (Chr: 6)
    CITATIONS (37)