ZFIN ID: ZDB-GENE-050105-5
Gene Name: solute carrier family 17 member 7a
Gene Symbol: slc17a7a    Nomenclature History

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Previous Names: slc17a7, vglut1 (3)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have L-glutamate transmembrane transporter activity. Predicted to be involved in several processes, including glutamatergic synaptic transmission; neurotransmitter loading into synaptic vesicle; and regulation of synapse structure or activity. Predicted to localize to excitatory synapse and integral component of synaptic vesicle membrane. Is expressed in nervous system and otic vesicle. Orthologous to human SLC17A7 (solute carrier family 17 member 7).
Genome Resources: Alliance (1),  Gene:795293 (1),  Ensembl(GRCz11):ENSDARG00000016480 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16454 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-slc17a7a N/A 2
    DISEASE ASSOCIATED WITH slc17a7a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc17a7a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transmembrane transporter activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc17a7a-201 (1)    Ensembl 1820
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-slc17a7 polyclonal Rabbit IHC, WB 11
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc17a7a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:slc17a7a-PAFMA,myl7:EGFP) hsp70lmyl7 EGFPPAslc17a7aTagRFP Danio rerio 1 1
    Tg(hsp70l:slc17a7a-pHGFP,myl7:EGFP) hsp70lmyl7 EGFPpHGFPslc17a7a Danio rerio 1 1
    MARKER RELATIONSHIPS
    slc17a7a Contained in: [BAC] DKEY-29B22 (1) (order this)
    slc17a7a Encodes: [cDNA] MGC:163045 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001098755 (1) 1820 nt
    Genomic GenBank:CR847509 (1) 157983 nt
    Select Tool
    Polypeptide UniProtKB:A3QK31 (1) 582 aa
    Sequence Information (all 13)
    ORTHOLOGY for slc17a7a ( Chr: 3 )
    CITATIONS (42)