Gene

slc26a3.1

ID
ZDB-GENE-041210-180
Name
solute carrier family 26 member 3
Symbol
slc26a3.1 Nomenclature History
Previous Names
  • slc26a3
  • si:dkey-31f5.2
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Exhibits sodium:bicarbonate symporter activity. Involved in anion homeostasis; chloride transport; and response to salt stress. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in congenital secretory chloride diarrhea 1 and diarrhea. Is expressed in several structures, including gill; heart; lateral line system; liver; and pleuroperitoneal region. Orthologous to human SLC26A3 (solute carrier family 26 member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Bayaa et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc26a3.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital secretory chloride diarrhea 1 Alliance Diarrhea 1, secretory chloride, congenital 214700
Associated With slc26a3.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018045 Sulphate anion transporter, conserved site
Domain IPR002645 STAS domain
Domain IPR011547 SLC26A/SulP transporter domain
Family IPR001902 SLC26A/SulP transporter
Family IPR030321 Solute carrier family 26 member 3 (DRA)
Homologous_superfamily IPR036513 STAS domain superfamily
Domain Details Per Protein
Protein Length SLC26A/SulP transporter SLC26A/SulP transporter domain Solute carrier family 26 member 3 (DRA) STAS domain STAS domain superfamily Sulphate anion transporter, conserved site
UniProtKB:Q5RGV3 572
UniProtKB:B6DUH7 745
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-slc26a3 polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations