ZFIN ID: ZDB-GENE-041210-180
Gene Name: solute carrier family 26 member 3
Gene Symbol: slc26a3.1    Nomenclature History

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Previous Names: slc26a3, si:dkey-31f5.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Exhibits sodium:bicarbonate symporter activity. Involved in anion homeostasis; chloride transport; and response to salt stress. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including gill; heart; lateral line system; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in congenital secretory chloride diarrhea 1 and diarrhea. Orthologous to human SLC26A3 (solute carrier family 26 member 3).
Genome Resources: Alliance (1),  Gene:563962 (1),  Ensembl(GRCz11):ENSDARG00000007371 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-slc26a3.1 N/A 1
PHENOTYPE
Data: Fig. 11 from Bayaa et al., 2009
Observed in:
DISEASE ASSOCIATED WITH slc26a3.1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital secretory chloride diarrhea 1 Alliance Diarrhea 1, secretory chloride, congenital 214700
DISEASE ASSOCIATED WITH slc26a3.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anion homeostasis (more)
Cellular Component integral component of membrane (more)
Molecular Function sodium:bicarbonate symporter activity (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA slc26a3.1-202 (1)    Ensembl 1718
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-slc26a3 polyclonal Rabbit IHC 1
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM slc26a3.1 No data available
MARKER RELATIONSHIPS
slc26a3.1 Contained in: [BAC] DKEY-31F5 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001135683 (1) 2238 nt
Genomic GenBank:BX649534 (1) 205347 nt Blast at MegaBLAST
Polypeptide UniProtKB:B6DUH7 (1) 745 aa
Sequence Information (all 13)
ORTHOLOGY for slc26a3.1 ( Chr: 4 )
CITATIONS (19)