ZFIN ID: ZDB-GENE-041111-261
Gene Name: NADH:ubiquinone oxidoreductase core subunit S7
Gene Symbol: ndufs7    Nomenclature History

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Previous Names: fj19d10, im:7149436, wu:fj19d10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration; electron transport coupled proton transport; and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrial respiratory chain complex I. Is expressed in several structures, including eye; immature eye; musculature system; optic tectum; and pharyngeal arch 3-7 skeleton. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7).
Genome Resources: Alliance (1),  Gene:796997 (1),  Ensembl(GRCz11):ENSDARG00000074552 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [IMAGE:7149436]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ndufs7 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mitochondrial complex I deficiency, nuclear type 3 618224
DISEASE ASSOCIATED WITH ndufs7 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component mitochondrial respiratory chain complex I (more)
Molecular Function 4 iron, 4 sulfur cluster binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ndufs7-201 (1)    Ensembl 948
ndufs7-202 (1)    Ensembl 884
ncRNA ndufs7-002 (1)    Ensembl 849
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ndufs7 No data available
MARKER RELATIONSHIPS
ndufs7 Contained in: [BAC] CH211-248I1 (1)
ndufs7 Encodes: [EST] fj19d10, IMAGE:7149436 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001199912 (1) 949 nt
Genomic GenBank:BX323045 (1) 104629 nt
Select Tool
Polypeptide UniProtKB:A0A0R4ILG5 (1) 246 aa
Sequence Information (all 13)
ORTHOLOGY for ndufs7 ( Chr: 11 )
CITATIONS (16)