Gene
slc25a18
- ID
- ZDB-GENE-041111-192
- Name
- solute carrier family 25 member 18
- Symbol
- slc25a18 Nomenclature History
- Previous Names
-
- im:7143718
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to act upstream of or within transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to human SLC25A18 (solute carrier family 25 member 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial Solute Carrier | Mitochondrial substrate/solute carrier |
|---|---|---|---|---|---|---|
| UniProtKB:E7F2B8 | InterPro | 324 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc25a18-201
(1)
|
Ensembl | 1,698 nt | ||
| mRNA |
slc25a18-202
(1)
|
Ensembl | 3,919 nt | ||
| mRNA |
slc25a18-203
(1)
|
Ensembl | 882 nt | ||
| mRNA |
slc25a18-204
(1)
|
Ensembl | 1,486 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-266K8 | ZFIN Curated Data | |
| Contained in | BAC | CH211-276C7 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7143718 | Thisse et al., 2004 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005174363 (1) | 2906 nt | ||
| Genomic | GenBank:CR376785 (1) | 173989 nt | ||
| Polypeptide | UniProtKB:E7F2B8 (1) | 324 aa |
- Dai, X., Pradhan, A., Liu, J., Liu, R., Zhai, G., Zhou, L., Dai, J., Shao, F., Yuan, Z., Wang, Z., Yin, Z. (2023) Zebrafish gonad mutant models reveal neuroendocrine mechanisms of brain sexual dimorphism and male mating behaviors of different brain regions. Biology of sex differences. 14:5353
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Garcia-Reyero, N., Escalon, L., Prats, E., Faria, M., Soares, A.M., Raldúa, D. (2016) Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Bulletin of environmental contamination and toxicology. 96(6):707-713
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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