Gene
dpf2
- ID
- ZDB-GENE-041024-2
- Name
- double PHD fingers 2
- Symbol
- dpf2 Nomenclature History
- Previous Names
-
- im:7146797
- zgc:101789
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nBAF complex. Is expressed in brain; epiphysis; and spinal cord. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 7. Orthologous to human DPF2 (double PHD fingers 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Coffin-Siris syndrome 7 | Alliance | Coffin-Siris syndrome 7 | 618027 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR025750 | DPF1-3, N-terminal domain |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DPF1-3, N-terminal domain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5XJL8 | InterPro | 400 | |||||||
| UniProtKB:A0A8M3B9T0 | InterPro | 410 | |||||||
| UniProtKB:A0A8M9Q8I8 | InterPro | 324 | |||||||
| UniProtKB:A0A8M2BCR7 | InterPro | 414 |
Interactions and Pathways
No data available
Plasmids