Gene

dpf2

ID

ZDB-GENE-041024-2

Name

double PHD fingers 2

Symbol

dpf2 Nomenclature History

Previous Names

im:7146797
zgc:101789

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have histone acetyltransferase activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated; nervous system development; and positive regulation of transcription by RNA polymerase II. Predicted to localize to histone acetyltransferase complex and nBAF complex. Is expressed in brain; epiphysis; and spinal cord. Orthologous to human DPF2 (double PHD fingers 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:101789 (1 image)
IMAGE:7146797 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dpf2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Coffin-Siris syndrome 7	Alliance	Coffin-Siris syndrome 7	618027

Associated With dpf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR013087	Zinc finger C2H2-type
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR025750	DPF1-3, N-terminal domain
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036236	Zinc finger C2H2 superfamily

Domain Details Per Protein

Protein	Length	DPF1-3, N-terminal domain	Zinc finger C2H2 superfamily	Zinc finger C2H2-type	Zinc finger, FYVE/PHD-type	Zinc finger, PHD-finger	Zinc finger, PHD-type	Zinc finger, RING/FYVE/PHD-type
UniProtKB:Q5XJL8 InterPro	400
UniProtKB:A0A8M3B9T0 InterPro	410
UniProtKB:A0A8M9Q8I8 InterPro	324
UniProtKB:A0A8M2BCR7 InterPro	414

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dpf2-201 (1) Ensembl	Havana	1708 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	dpf2-203 (1) Ensembl	Havana	539 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	dpf2-205 (1) Ensembl	Havana	486 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	dpf2-004 (1) Ensembl	Havana	509 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	dpf2-005 (1) Ensembl	Havana	997 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	dpf2-006 (1) Ensembl	Havana	421 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations