Gene

ppp1r12a

ID
ZDB-GENE-041011-3
Name
protein phosphatase 1, regulatory subunit 12A
Symbol
ppp1r12a Nomenclature History
Previous Names
  • mypt1 (1)
  • myosin phosphatase targeting subunit 1 (1)
  • myosin-binding subunit of myosin phosphatase (1)
  • si:dkey-28j4.1 (1)
  • unm p82emcf
  • unm_p82emcf
  • zgc:110448 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity. Involved in several processes, including actin filament bundle organization; convergent extension involved in axis elongation; and nervous system development. Localizes to cytoplasm. Is expressed in several structures, including central nervous system; digestive system; endoderm; mesoderm; and myotome. Orthologous to several human genes including PPP1R12A (protein phosphatase 1 regulatory subunit 12A).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
26 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppp1r12a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Genitourinary and/or/brain malformation syndrome 618820
Associated With ppp1r12a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020683 Ankyrin repeat-containing domain
Domain IPR031775 cGMP-dependent protein kinase, interacting domain
Family IPR017401 Protein phosphatase 1 regulatory subunit 12A/B/C
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily cGMP-dependent protein kinase, interacting domain Protein phosphatase 1 regulatory subunit 12A/B/C
UniProtKB:Q6DRG7 1049
UniProtKB:Z4YIS0 1117
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations