Gene
ppp1r12a
- ID
- ZDB-GENE-041011-3
- Name
- protein phosphatase 1, regulatory subunit 12A
- Symbol
- ppp1r12a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Exhibits protein heterodimerization activity. Involved in several processes, including actin filament bundle organization; convergent extension involved in axis elongation; and nervous system development. Localizes to cytoplasm. Is expressed in several structures, including central nervous system; digestive system; endoderm; mesoderm; and myotome. Orthologous to several human genes including PPP1R12A (protein phosphatase 1 regulatory subunit 12A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 32 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Genitourinary and/or/brain malformation syndrome | 618820 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR020683 | Ankyrin repeat-containing domain |
Domain | IPR031775 | cGMP-dependent protein kinase, interacting domain |
Family | IPR017401 | Protein phosphatase 1 regulatory subunit 12A/B/C |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain | Ankyrin repeat-containing domain superfamily | cGMP-dependent protein kinase, interacting domain | Protein phosphatase 1 regulatory subunit 12A/B/C |
---|---|---|---|---|---|---|
UniProtKB:Q6DRG7
|
1049 | |||||
UniProtKB:Z4YIS0
|
1117 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
ppp1r12a-201
(1)
|
4846 nt | |
mRNA | ppp1r12a-tv201 (1) | 3313 nt | |
mRNA | ppp1r12a-tv202 (1) | 3032 nt |
Interactions and Pathways
No data available
Plasmids
No data available