ZFIN ID: ZDB-GENE-041011-3
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Gene Name: protein phosphatase 1, regulatory subunit 12A
Gene Symbol: ppp1r12a
Sequence Ontology ID : SO:0000704

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Previous Names: mypt1 (1), myosin phosphatase targeting subunit 1 (1), myosin-binding subunit of myosin phosphatase (1), si:dkey-28j4.1 (1), unm p82emcf, unm_p82emcf, zgc:110448 (1)

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein heterodimerization activity; involved in several processes, including actin filament bundle organization, animal organ development, and convergent extension involved in axis  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2653Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la024489Tg Transgenic Insertion Unknown Unknown DNA
    la024490Tg Transgenic Insertion Unknown Unknown DNA
    la024491Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • p82emcf Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa15933 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa20271 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa20272 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa25279 Point Mutation Unknown Premature Stop ENU
    sq181 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: 24 figures from 8 publications
    Observed in:
    DISEASE ASSOCIATED WITH ppp1r12a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp1r12a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension involved in axis elongation (more)
    Cellular Component A band (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002110 (1)
  • InterPro:IPR017401 (1)
  • InterPro:IPR020683 (1)
  • InterPro:IPR031775 (1)
  • InterPro:IPR036770 (1)
    		•
  • PROSITE:PS50088 (1)
  • PROSITE:PS50297 (1)
    		•
  • Pfam:PF12796 (1)
  • Pfam:PF15898 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ppp1r12a-001 (1) 4846
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ppp1r12a No data available
    MARKER RELATIONSHIPS
    ppp1r12aContained in: [BAC] DKEY-28J4 (1) (order this)
    ppp1r12aEncodes: [cDNA] MGC:110448 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003870 (1) 3322bp
    Select Tool
    Genomic GenBank:BX537286 (1) 179930bp
    Select Tool
    Polypeptide UniProtKB:Z4YIS0 (1) 1117aa
    Select Tool
    Sequence Clusters UniGene:133094 (1)
    Sequence Information (all 26)
    OTHER ppp1r12a GENE PAGES
  • Alliance (1)
  • Gene:445393 (1)
  • VEGA:OTTDARG00000008393 (1)
  • Ensembl(GRCz11):ENSDARG00000010784 (2)
    • ORTHOLOGY for ppp1r12a (Chr: 4)
    CITATIONS (48)