Gene

kng1

ID
ZDB-GENE-041010-56
Name
kininogen 1
Symbol
kng1 Nomenclature History
Previous Names
  • fb64g01
  • wu:fb64g01 (1)
  • zgc:103569
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase inhibitor activity. Involved in cranial skeletal system development. Predicted to localize to extracellular region. Is expressed in liver. Human ortholog(s) of this gene implicated in high molecular weight kininogen deficiency. Orthologous to human KNG1 (kininogen 1).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Jacox et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kng1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
high molecular weight kininogen deficiency Alliance [High molecular weight kininogen deficiency] 228960
high molecular weight kininogen deficiency Alliance [Kininogen deficiency] 228960
Associated With kng1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000010 Cystatin domain
Domain IPR027358 Kininogen-type cystatin domain
Domain Details Per Protein
Protein Length Cystatin domain Kininogen-type cystatin domain
UniProtKB:Q5XJ76 331
UniProtKB:E9QEH2 158
UniProtKB:E9QFM6 104
UniProtKB:Q1LYJ7 331
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations