ZFIN ID: ZDB-GENE-040914-66
Gene Name: thioredoxin reductase 2, tandem duplicate 2
Gene Symbol: txnrd2.2
Sequence Ontology ID : SO:0000704

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Previous Names: im:7135991 (1), si:ch1073-179p4.3

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have thioredoxin-disulfide reductase activity; predicted to be involved in cell redox homeostasis; predicted to localize to the mitochondrion; orthologous to human TXNRD2 (thioredoxin  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7135991]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20364 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40377 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH txnrd2.2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ?Glucocorticoid deficiency 5 617825
    ?Glucocorticoid deficiency 5 617825
    DISEASE ASSOCIATED WITH txnrd2.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell redox homeostasis (more)
    Cellular Component mitochondrion (more)
    Molecular Function electron transfer activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001100 (1)
  • InterPro:IPR004099 (1)
  • InterPro:IPR006338 (1)
  • InterPro:IPR012999 (1)
  • InterPro:IPR016156 (1)
  • InterPro:IPR023753 (1)
  • InterPro:IPR036188 (1)
  • PROSITE:PS00076 (1)
  • Pfam:PF02852 (1)
  • Pfam:PF07992 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA si:ch1073-179p4.3-001 (1) 1179
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM txnrd2.2 No data available
    MARKER RELATIONSHIPS
    txnrd2.2Contained in: [Fosmid] CH1073-179P4 (1) (order this)
    txnrd2.2Encodes: [EST] IMAGE:7135991 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001353394 (1)
    Genomic GenBank:CR847528 (1) 101837bp
    Select Tool
    Polypeptide UniProtKB:F1Q6Z6 (1) 515aa
    Sequence Information (all 15)
    OTHER txnrd2.2 GENE PAGES
  • Alliance (1)
  • Gene:798259 (1)
  • VEGA:OTTDARG00000033297 (1)
  • Ensembl(GRCz11):ENSDARG00000075923 (1)
  • ORTHOLOGY for txnrd2.2 (Chr: 5)
    CITATIONS (15)