ZFIN ID: ZDB-GENE-040912-169
Gene Name: acyl-CoA synthetase long chain family member 5
Gene Symbol: acsl5    Nomenclature History

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Previous Name: zgc:92083

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have arachidonate-CoA ligase activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in several processes, including long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; and positive regulation of long-chain fatty acid import across plasma membrane. Predicted to localize to endoplasmic reticulum; membrane; and mitochondrion. Is expressed in brain; gill; liver; pleuroperitoneal region; and yolk syncytial layer. Orthologous to human ACSL5 (acyl-CoA synthetase long chain family member 5).
Genome Resources: Alliance (1),  Gene:447860 (1),  Ensembl(GRCz11):ENSDARG00000075931 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:92083]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7163345]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6263 Point Mutation Unknown Splice Site ENU
sa42064 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acsl5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acsl5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lipid biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acsl5-202 (1)    Ensembl 3394
    acsl5-203 (1)    Ensembl 762
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acsl5 No data available
    MARKER RELATIONSHIPS
    acsl5 Contained in: [BAC] CH73-167A11 (1)
    acsl5 Encodes: [EST] IMAGE:7163345 (1)
    [cDNA] MGC:92083 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004599 (1) 3138 nt
    Genomic GenBank:CU459185 (1) 132093 nt
    Select Tool
    Polypeptide UniProtKB:F1RAK0 (1) 681 aa
    Sequence Information (all 14)
    ORTHOLOGY for acsl5 ( Chr: 12 )
    CITATIONS (24)