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ZIRC
ZFIN ID: ZDB-GENE-040912-152
Gene Name: histidyl-tRNA synthetase
Gene Symbol: hars
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: im:7136719, zgc:92215 (1)

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have histidine-tRNA ligase activity and identical protein binding activity; involved in regulation of vasculature development and sprouting angiogenesis; localizes to the mitochondrion;  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7136719]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cq34 Point Mutation Intron 7 Exon Loss ENU
la019111Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH hars HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease, axonal type 2W Charcot-Marie-Tooth disease, axonal, type 2W 616625
    Perrault syndrome ?Perrault syndrome 2 614926
    Usher syndrome type 3B Usher syndrome type 3B 614504
    DISEASE ASSOCIATED WITH hars VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of vasculature development (more)
    Cellular Component cytoplasm (more)
    Molecular Function aminoacyl-tRNA ligase activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hars-201 (1) 2081
    hars-202 (1) 1817
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hars No data available
    MARKER RELATIONSHIPS
    harsContained in: [BAC] CH211-235C4 (1) (order this)
    harsEncodes: [EST] IMAGE:7136719 (1) (order this)
    [cDNA] MGC:92215 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001302256 (1)
    Genomic GenBank:BX890575 (1) 204730bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q5D5 (1) 520aa
    Sequence Clusters UniGene:76966 (1)
    Sequence Information (all 19)
    ORTHOLOGY for hars (Chr: 14)
    CITATIONS (27)