Gene

cox6a2

ID
ZDB-GENE-040912-129
Name
cytochrome c oxidase subunit 6A2
Symbol
cox6a2 Nomenclature History
Previous Names
  • zgc:103594 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to localize to mitochondrial respiratory chain complex IV. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D and cytochrome-c oxidase deficiency disease. Orthologous to several human genes including COX6A2 (cytochrome c oxidase subunit 6A2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cox6a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mitochondrial complex IV deficiency, nuclear type 18 619062
Associated With cox6a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018507 Cytochrome c oxidase, subunit VIa, conserved site
Family IPR001349 Cytochrome c oxidase, subunit VIa
Homologous_superfamily IPR036418 Cytochrome c oxidase, subunit VIa superfamily
Domain Details Per Protein
Protein Length Cytochrome c oxidase, subunit VIa Cytochrome c oxidase, subunit VIa, conserved site Cytochrome c oxidase, subunit VIa superfamily
UniProtKB:Q66I77 103
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations