Gene

crlf1a

ID
ZDB-GENE-040718-397
Name
cytokine receptor-like factor 1a
Symbol
crlf1a Nomenclature History
Previous Names
  • clf-1a (1)
  • crlf1
  • fd24a10
  • wu:fd24a10
  • zgc:91992 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to CRLF-CLCF1 complex; external side of plasma membrane; and receptor complex. Is expressed in diencephalon; hypothalamus; optic tectum; and telencephalon. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 1. Orthologous to human CRLF1 (cytokine receptor like factor 1).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With crlf1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cold-induced sweating syndrome 1 Alliance Cold-induced sweating syndrome 1 272430
Associated With crlf1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR010457 Immunoglobulin C2-set-like, ligand-binding
Domain IPR015152 Growth hormone/erythropoietin receptor, ligand binding
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Growth hormone/erythropoietin receptor, ligand binding Immunoglobulin C2-set-like, ligand-binding Immunoglobulin-like domain superfamily Immunoglobulin-like fold
UniProtKB:Q6DG28 389
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations