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ZIRC
ZFIN ID: ZDB-GENE-040718-157
Gene Name: EGF-like-domain, multiple 6
Gene Symbol: egfl6    Nomenclature History

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Previous Names: cb3 (1), maeg (1), sb:cb3, wu:fc66b04, zgc:92328

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in notochord development; positive regulation of sprouting angiogenesis; and regulation of Notch signaling pathway. Predicted to localize to the membrane. Is expressed in several structures, including fin; median fin fold; pharyngeal arch; rhombomere; and somite. Orthologous to human EGFL6 (EGF like domain multiple 6).
Genome Resources: Alliance (1),  Gene:436730 (1),  Ensembl(GRCz11):ENSDARG00000045958 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6120 Point Mutation Unknown Premature Stop ENU
sa21615 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf772 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
    zf773 Insertion Exon 1 Frameshift, Premature Stop TALEN
    zf774 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-egfl6 N/A 2
    MO2-egfl6 N/A 1
    TALEN1-egfl6 1
    DISEASE ASSOCIATED WITH egfl6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH egfl6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of sprouting angiogenesis (more)
    Cellular Component membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA egfl6-202 (1)    Ensembl 353
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-egfl6 monoclonal Mouse IHC 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM egfl6 No data available
    MARKER RELATIONSHIPS
    egfl6 Contained in: [Fosmid] CH1073-491K19 (1) (order this)
    egfl6 Encodes: [EST] cb3 (1) (order this), fc66b04
    [cDNA] MGC:92328 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002457 (1) 1983 bp
    Genomic GenBank:FO834809 (1) 38340 bp
    Select Tool
    Polypeptide UniProtKB:Q6DHG1 (1) 508 aa
    Sequence Clusters UniGene:150487 (1)
    Sequence Information (all 25)
    ORTHOLOGY for egfl6 ( Chr: 9 )
    CITATIONS (22)