ZFIN ID: ZDB-GENE-040622-1
Gene Name: zic family member 5 (odd-paired homolog, Drosophila)
Gene Symbol: zic5    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in nervous system development and regulation of cell population proliferation. Predicted to localize to nucleus. Is expressed in several structures, including apical ectodermal ridge pectoral fin bud; central nervous system; lateral plate mesoderm; neural plate; and optic vesicle. Orthologous to human ZIC5 (Zic family member 5).
Genome Resources: Alliance (1),  Gene:403041 (1),  Ensembl(GRCz11):ENSDARG00000016022 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010776Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026900Tg Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-zic5 N/A 2
    MO2-zic5 N/A 1
    DISEASE ASSOCIATED WITH zic5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH zic5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell proliferation in midbrain (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zic5-201 (1)    Ensembl 2587
    ncRNA zic5-002 (1) 1887
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zic5 No data available
    MARKER RELATIONSHIPS
    zic5 Contained in: [BAC] CH211-277G23 (1)
    zic5 Encodes: [EST] eu548 (1), IMAGE:7157050 (1)
    [cDNA] MGC:193830 (1), MGC:193860 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205727 (1) 2599 nt
    Genomic GenBank:BX469902 (1) 179135 nt
    Select Tool
    Polypeptide UniProtKB:Q6VUB8 (1) 497 aa
    Sequence Information (all 18)
    ORTHOLOGY for zic5 ( Chr: 9 )
    CITATIONS (33)