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ZIRC
ZFIN ID: ZDB-GENE-040426-847
Gene Name: histone deacetylase 3
Gene Symbol: hdac3    Nomenclature History

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Previous Name: zgc:55927 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity; histone deacetylase activity; and transcription corepressor activity. Involved in several processes, including angiogenesis; liver development; and posterior lateral line development. Predicted to localize to the cytoplasm; histone deacetylase complex; and transcriptional repressor complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is expressed in several structures, including axial blood vessel; blood vessel; digestive system; otic vesicle; and sensory system. Orthologous to human HDAC3 (histone deacetylase 3).
Genome Resources: Alliance (1),  Gene:393965 (1),  Ensembl(GRCz11):ENSDARG00000037514 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2786aTg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22434 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35650 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hdac3 N/A 4
    MO2-hdac3 N/A 1
    MO3-hdac3 N/A 2
    DISEASE ASSOCIATED WITH hdac3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hdac3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component cytoplasm (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 23)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript hdac3-202 (1)    Ensembl 705
    mRNA hdac3-201 (1)    Ensembl 2138
    ottdart00000032801 (1) 2135
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hdac3 No data available
    MARKER RELATIONSHIPS
    hdac3 Contained in: [BAC] CH211-194M19 (1) (order this)
    [PAC] BUSM1-87D10 (1) (order this)
    hdac3 Encodes: [cDNA] MGC:55927 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200990 (1) 2069 bp
    Genomic GenBank:BX927254 (1) 152687 bp
    Select Tool
    Polypeptide UniProtKB:F1RCG9 (1) 428 aa
    Sequence Clusters UniGene:80607 (1)
    Sequence Information (all 13)
    ORTHOLOGY for hdac3 ( Chr: 14 )
    CITATIONS (48)