ZFIN ID: ZDB-GENE-040426-2854
Gene Name: Mtr4 exosome RNA helicase
Gene Symbol: mtrex    Nomenclature History

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Previous Names: mtrex, julie (1), skiv2l2, wu:fd11a05, zgc:63838

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have RNA helicase activity. Involved in fin regeneration and positive regulation of cell division. Predicted to localize to the nucleus. Is expressed in blastomere; nervous system; and pectoral fin. Orthologous to human MTREX (Mtr4 exosome RNA helicase).
Genome Resources: Alliance (1),  Gene:406795 (1),  Ensembl(GRCz11):ENSDARG00000013457 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
j24e1 Point Mutation Donor Splice Site of Exon 11 Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011666Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21658 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21659 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH mtrex HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mtrex VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fin regeneration (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001650 Helicase, C-terminal
    Domain IPR011545 DEAD/DEAH box helicase domain
    Domain IPR012961 ATP-dependent RNA helicase Ski2, C-terminal
    Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
    Family IPR016438 ATP-dependent RNA helicase Ski2-like
    Domain IPR025696 rRNA-processing arch domain
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mtrex-201 (1)    Ensembl 3333
    ncRNA skiv2l2-002 (1)    Ensembl 535
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mtrex No data available
    MARKER RELATIONSHIPS
    mtrex Contained in: [BAC] CH73-96J23 (1)
    mtrex Encodes: [EST] fd11a05 (1)
    [cDNA] MGC:63838 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214768 (1) 3334 bp
    Genomic GenBank:CU929245 (1) 102610 bp
    Select Tool
    Polypeptide UniProtKB:F1QD61 (1) 1034 aa
    Sequence Information (all 11)
    ORTHOLOGY for mtrex ( Chr: 10 )
    CITATIONS (24)