Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2795
Gene Name: retinitis pigmentosa 2 (X-linked recessive)
Gene Symbol: rp2
Previous Names: nme10 (1), wu:fj10e02, wu:fm72d05, zgc:55632
Location: Chr: 6   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 6 publications
Directly Submitted Expression Data: 4 figures (9 images) from Rauch et al., 2003 [MGC:55632]
  1 figure (1 image) from Thisse et al., 2004 [MGC:55632]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, eye, gill, gut (all 21) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa17284
Knockdown reagents: MO1-rp2 (1), MO2-rp2 (1), MO3-rp2 (1), MO4-rp2 (1), MO5-rp2 (1)
PHENOTYPE
Data: 7 figures from 3 publications
Observed in: apoptotic process, brain, determination of heart left/right asymmetry, extension (all 21) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Retinitis pigmentosa 2 312600
GENE ONTOLOGY
Ontology GO Term
Biological Process pronephros development (more)
Molecular Function ATP binding (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001564 (1)
  • InterPro:IPR006599 (1)
  • InterPro:IPR012945 (1)
  • InterPro:IPR013912 (1)
  • InterPro:IPR016098 (1)
  • InterPro:IPR017332 (1)
  • InterPro:IPR017901 (1)
  • PROSITE:PS51329 (1)
  • Pfam:PF00334 (1)
  • Pfam:PF07986 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rp2-001 (1) 2148
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-rp2 (1), Ab2-rp2 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rp2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rp2 Contained in: [BAC] DKEY-62E6 (1)
    rp2 Encodes: [EST] fj10e02, fm72d05 (1)
    [cDNA] MGC:55632 (1) (order this), MGC:192020 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213446 (1) 2020 bp
    Genomic GenBank:BX322552 (1) 230846 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1D694 (1) 376 aa
    Sequence Clusters UniGene:80773 (1)
    Sequence Information (all 25)
    OTHER rp2 GENE PAGES
  • Gene:406755 (1)
  • VEGA:OTTDARG00000019882 (1)
  • Ensembl(Zv9):ENSDARG00000044339 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish rp2 6  
    Human RP2 X (Xp11.3)
  • OMIM:300757
  • Gene:6102
  • Mouse Rp2h X ( 15.83 cM)
  • MGI:1277953
  • Gene:19889
  • Orthology Details
    CITATIONS (22)