ZFIN Gene: vrk1

ZFIN ID: ZDB-GENE-040426-2709

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Gene Name:	vaccinia related kinase 1
Gene Symbol:	vrk1
Previous Names:	wu:fe16f06, zgc:56266
Location:	Ambiguous Mapping Details/Browsers
Nomenclature History

GENE EXPRESSION
Directly Submitted Expression Data:	1 figure (1 image) from Thisse et al., 2004 [MGC:56266]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
	unspecified
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa23040	Point Mutation	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

DISEASE ASSOCIATED WITH vrk1 HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
pontocerebellar hypoplasia type 1A	Pontocerebellar hypoplasia type 1A	607596

GENE ONTOLOGY

Ontology	GO Term
Biological Process	Golgi disassembly (more)
Cellular Component	Golgi stack (more)
Molecular Function	ATP binding (more)

GO Terms (all 17)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000719 (1) InterPro:IPR008271 (1) InterPro:IPR011009 (1) InterPro:IPR017441 (1)	PROSITE:PS00107 (1) PROSITE:PS00108 (1) PROSITE:PS50011 (1)	Pfam:PF00069 (1)	EC:2.7.11.1 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
pseudogenic transcript	ottdart00000046472 (1)	1275	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
mRNA	vrk1-001 (1)	1542	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
ncRNA	vrk1-002 (1)	448	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

vrk1Contained in:	[BAC] CH73-218C12 (1) (order this), CH211-135E15 (1) (order this) [Fosmid] CH1073-432E22 (1) (order this)
vrk1Encodes:	[EST] fe16f06 (1) [cDNA] MGC:56266 (1) (order this), MGC:174836 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_213385 (1)	1562bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:CU467823 (1)	135288bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A7MCR4 (1)	425aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:77494 (1)

Sequence Information (all 18)

ORTHOLOGY for vrk1 (Ambiguous)

Species	Symbol	Chromosome	Accession #	Evidence
Human	VRK1	14	Gene:7443 OMIM:602168 HGNC:12718	Amino acid sequence comparison (1)

Download Curated Orthology