Gene
vrk1
- ID
- ZDB-GENE-040426-2709
- Name
- VRK serine/threonine kinase 1
- Symbol
- vrk1 Nomenclature History
- Previous Names
-
- wu:fe16f06
- zgc:56266
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in Golgi disassembly; Wnt signaling pathway; and peptidyl-serine phosphorylation. Predicted to localize to Golgi stack and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56266 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pontocerebellar hypoplasia type 1A | Alliance | Pontocerebellar hypoplasia type 1A | 607596 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:F1QA55
|
425 | ||||
|
UniProtKB:A7MCR4
|
425 | ||||
|
UniProtKB:Q7ZUS1
|
425 |
Interactions and Pathways
No data available
Plasmids
No data available