Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2709
Gene Name: vaccinia related kinase 1
Gene Symbol: vrk1
Previous Names: wu:fe16f06, zgc:56266
Location: Chr: 17   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56266]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa23040
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Pontocerebellar hypoplasia type 1A 607596
GENE ONTOLOGY
Ontology GO Term
Biological Process Golgi disassembly (more)
Cellular Component Golgi stack (more)
Molecular Function ATP binding (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • EC:2.7.11.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA vrk1-001 (1) 1542
    ncRNA vrk1-002 (1) 448
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vrk1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    vrk1 Contained in: [BAC] CH211-135E15 (1) (order this)
    [Fosmid] CH1073-432E22 (1) (order this)
    vrk1 Encodes: [EST] fe16f06 (1)
    [cDNA] MGC:56266 (1) (order this), MGC:174836 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213385 (1) 1562 bp
    Genomic GenBank:CU467823 (1) 135288 bp
    Select Tool
    Polypeptide UniProtKB:A7MCR4 (1) 425 aa
    Sequence Clusters UniGene:77494 (1)
    Sequence Information (all 19)
    OTHER vrk1 GENE PAGES
  • Gene:406694 (1)
  • VEGA:OTTDARG00000035003 (1)
  • Ensembl(Zv9):ENSDARG00000018006 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish vrk1 17  
    Human VRK1 14 (14q32)
  • OMIM:602168
  • Gene:7443
  • Orthology Details
    CITATIONS (17)