Gene

vrk1

ID
ZDB-GENE-040426-2709
Name
VRK serine/threonine kinase 1
Symbol
vrk1 Nomenclature History
Previous Names
  • wu:fe16f06
  • zgc:56266
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in Golgi disassembly; peptidyl-serine phosphorylation; and signal transduction. Predicted to act upstream of or within cell division and protein phosphorylation. Predicted to be located in Golgi stack. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vrk1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pontocerebellar hypoplasia type 1A Alliance Pontocerebellar hypoplasia type 1A 607596
Associated With vrk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:F1QA55 425
UniProtKB:A7MCR4 425
UniProtKB:Q7ZUS1 425
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations