Gene
vrk1
- ID
- ZDB-GENE-040426-2709
- Name
- VRK serine/threonine kinase 1
- Symbol
- vrk1 Nomenclature History
- Previous Names
-
- wu:fe16f06
- zgc:56266
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in Golgi disassembly; peptidyl-serine phosphorylation; and signal transduction. Predicted to act upstream of or within cell division and protein phosphorylation. Predicted to be located in Golgi stack. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56266 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pontocerebellar hypoplasia type 1A | Alliance | Pontocerebellar hypoplasia type 1A | 607596 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:F1QA55
|
425 | ||||
|
UniProtKB:A7MCR4
|
425 | ||||
|
UniProtKB:Q7ZUS1
|
425 |
Interactions and Pathways
No data available
Plasmids
No data available