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ZIRC
ZFIN ID: ZDB-GENE-040426-2709
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Gene Name: VRK serine/threonine kinase 1
Gene Symbol: vrk1
Sequence Ontology ID : SO:0000704

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Previous Names: wu:fe16f06, zgc:56266

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Location: Ambiguous Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity and protein serine/threonine kinase activity; predicted to be involved in Golgi disassembly, peptidyl-serine phosphorylation, and peptidyl-threonine  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56266]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23040 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vrk1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    pontocerebellar hypoplasia type 1A Pontocerebellar hypoplasia type 1A 607596
    DISEASE ASSOCIATED WITH vrk1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Golgi disassembly (more)
    Cellular Component Golgi stack (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
    		•
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
    		•
  • Pfam:PF00069 (1)
    		•
  • EC:2.7.11.1 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA vrk1-002 (1) 448
    Select Tool
    mRNA vrk1-201 (1) 1542
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM vrk1 No data available
    MARKER RELATIONSHIPS
    vrk1Contained in: [BAC] CH211-135E15 (1) (order this)
    [Fosmid] CH1073-432E22 (1) (order this)
    vrk1Encodes: [EST] fe16f06 (1)
    [cDNA] MGC:56266 (1) (order this), MGC:174836 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213385 (1) 1562bp
    Select Tool
    Genomic GenBank:CU467823 (1) 135288bp
    Select Tool
    Polypeptide UniProtKB:A7MCR4 (1) 425aa
    Select Tool
    Sequence Clusters UniGene:77494 (1)
    Sequence Information (all 19)
    OTHER vrk1 GENE PAGES
  • Alliance (1)
  • Gene:406694 (1)
  • VEGA:OTTDARG00000035003 (1)
  • Ensembl(GRCz11):ENSDARG00000018006 (1)
    • ORTHOLOGY for vrk1 (Ambiguous)
    CITATIONS (21)