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Gene

usp5

ID
ZDB-GENE-040426-2584
Name
ubiquitin specific peptidase 5 (isopeptidase T)
Symbol
usp5 Nomenclature History
Previous Names
  • wu:fa06b05 (1)
  • wu:fb36d11 (1)
  • wu:fc21h02 (1)
  • wu:fi41g10 (1)
  • zgc:76990 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable cysteine-type endopeptidase activity and thiol-dependent deubiquitinase. Involved in negative regulation of viral genome replication. Acts upstream of or within cranial skeletal system development and dorsal/ventral pattern formation. Located in cytoplasm. Orthologous to human USP5 (ubiquitin specific peptidase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp5 Human Ortholog
No data available
Associated With usp5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR001607 Zinc finger, UBP-type
Domain IPR015940 Ubiquitin-associated domain
Domain IPR028889 Ubiquitin specific protease domain
Domain IPR041432 Ubiquitinyl hydrolase, variant UBP zinc finger
Family IPR016652 Ubiquitinyl hydrolase
Homologous_superfamily IPR009060 UBA-like superfamily
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase UBA-like superfamily Ubiquitin-associated domain Ubiquitin specific protease, conserved site Ubiquitin specific protease domain Ubiquitinyl hydrolase Ubiquitinyl hydrolase, variant UBP zinc finger Zinc finger, RING/FYVE/PHD-type Zinc finger, UBP-type
UniProtKB:Q1MT86 853
UniProtKB:F8W4C4 834
UniProtKB:Q4V973 834
UniProtKB:Q6NY90 834
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations