ZFIN ID: ZDB-GENE-040426-2536
Gene Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
Gene Symbol: cdipt    Nomenclature History

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Previous Names: lop (1), zgc:77540 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity. Involved in several processes, including camera-type eye development; endoplasmic reticulum tubular network maintenance; and intestinal epithelial structure maintenance. Predicted to localize to Golgi apparatus. Is expressed in brain; digestive system; eye; and fin. Used to study fatty liver disease. Orthologous to human CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase).
Genome Resources: Alliance (1),  Gene:404620 (1),  Ensembl(GRCz11):ENSDARG00000070686 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi559Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la010472Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la010730Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023981Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nt9 Point Mutation Exon 3 Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cdipt N/A 1
    MO2-cdipt N/A 1
    MO3-cdipt N/A 2
    MO4-cdipt N/A 1
    MO5-cdipt N/A 2
    PHENOTYPE
    Data: 28 figures from 7 publications
    Observed in:
    DISEASE ASSOCIATED WITH cdipt HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdipt VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    fatty liver disease cdipthi559Tg/hi559Tg standard conditions (2)
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cdipt-201 (1)    Ensembl 1563
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cdipt polyclonal Rabbit IHC, WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdipt No data available
    MARKER RELATIONSHIPS
    cdipt Contained in: [BAC] DKEY-183N6 (1) (order this)
    cdipt Encodes: [cDNA] MGC:77540 (1), MGC:174794 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_207088 (1) 1527 nt
    Genomic GenBank:CR387996 (1) 210145 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6DRN8 (1) 213 aa
    Sequence Information (all 15)
    ORTHOLOGY for cdipt ( Chr: 3 )
    CITATIONS (42)