Gene

gcdha

ID
ZDB-GENE-040426-1855
Name
glutaryl-CoA dehydrogenase a
Symbol
gcdha Nomenclature History
Previous Names
  • gcdh
  • zgc:77704 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have fatty-acyl-CoA binding activity; flavin adenine dinucleotide binding activity; and glutaryl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase and fatty-acyl-CoA biosynthetic process. Is expressed in alar plate midbrain region; eye; immature eye; musculature system; and optic tectum. Human ortholog(s) of this gene implicated in glutaric acidemia I. Orthologous to human GCDH (glutaryl-CoA dehydrogenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gcdha Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
glutaric acidemia I Alliance Glutaricaciduria, type I 231670
Associated With gcdha Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006089 Acyl-CoA dehydrogenase, conserved site
Domain IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Domain IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
Domain IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
Homologous_superfamily IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Homologous_superfamily IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
Homologous_superfamily IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA dehydrogenase, conserved site Acyl-CoA dehydrogenase-like, C-terminal Acyl-CoA dehydrogenase/oxidase C-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily Acyl-CoA oxidase/dehydrogenase, central domain
UniProtKB:Q6P3I8 441
UniProtKB:A0A2R8Q208 361
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations