ZFIN ID: ZDB-GENE-040426-1716
Gene Name: ribosomal protein S19
Gene Symbol: rps19    Nomenclature History

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Previous Name: zgc:73211 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Contributes as a structural constituent of ribosome. Involved in several processes, including brain segmentation; erythrocyte development; and hemoglobin biosynthetic process. Localizes to ribosome. Used to study Diamond-Blackfan anemia and aplastic anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia. Orthologous to human RPS19 (ribosomal protein S19).
Genome Resources: Alliance (1),  Gene:393723 (1),  Ensembl(GRCz11):ENSDARG00000030602 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Danilova et al., 2008
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zf556 Indel Intron 2 - Exon 3 Splice Junction Unknown TALEN
zf557 Small Deletion Intron 2 - Exon 3 Splice Junction Unknown TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-rps19 N/A 10
MO2-rps19 N/A 4
TALEN1-rps19 1
DISEASE ASSOCIATED WITH rps19 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Diamond-Blackfan anemia 1 Alliance Diamond-Blackfan anemia 1 105650
GENE ONTOLOGY
Ontology GO Term
Biological Process intrinsic apoptotic signaling pathway by p53 class mediator (more)
Cellular Component ribosome (more)
Molecular Function CONTRIBUTES_TO   structural constituent of ribosome (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rps19-201 (1)    Ensembl 631
rps19-202 (1)    Ensembl 861
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rps19 No data available
MARKER RELATIONSHIPS
rps19 Contained in: [BAC] CH211-213B7 (1)
rps19 Encodes: [cDNA] MGC:73211 (1), MGC:173970 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200750 (1) 492 nt
Genomic GenBank:CR391920 (1) 199710 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IJ49 (1) 152 aa
Sequence Information (all 14)
ORTHOLOGY for rps19 ( Chr: 16 )
CITATIONS (35)