Gene
rps19
- ID
- ZDB-GENE-040426-1716
- Name
- ribosomal protein S19
- Symbol
- rps19 Nomenclature History
- Previous Names
-
- zgc:73211 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Contributes as a structural constituent of ribosome. Acts upstream of or within several processes, including brain segmentation; erythrocyte development; and hemoglobin biosynthetic process. Located in ribosome. Used to study Diamond-Blackfan anemia and aplastic anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia and Diamond-Blackfan anemia 1. Orthologous to human RPS19 (ribosomal protein S19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Danilova et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 32 figures from 15 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diamond-Blackfan anemia 1 | Alliance | Diamond-Blackfan anemia 1 | 105650 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018277 | Small ribosomal subunit protein eS19, conserved site |
| Family | IPR001266 | Small ribosomal subunit protein eS19 |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Small ribosomal subunit protein eS19 | Small ribosomal subunit protein eS19, conserved site | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6PBW7 | InterPro PDB | 146 |
Interactions and Pathways
No data available
Plasmids