ZFIN ID: ZDB-GENE-040426-1664
Gene Name: phosphodiesterase 6C, cGMP-specific, cone, alpha prime
Gene Symbol: pde6c
Sequence Ontology ID : SO:0000704

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Previous Names: eclipse (1), pde6 alpha prime (1), zgc:73085

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 10 figures from 8 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
  anatomical structure, epiphysis, eye, retina (all 8) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb73 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • ihb74 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • ihb75 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • rw76a Point Mutation Unknown Unknown ENU
    sa22017 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41953 Point Mutation Unknown Splice Site ENU
    w59 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-pde6c (1), MO1-pde6c (1)
    PHENOTYPE
    Data: 27 figures from 9 publications
    Observed in: anatomical structure, blue sensitive photoreceptor cell, cell proliferation, detection of light stimulus involved in visual perception (all 33) expand
    DISEASE ASSOCIATED WITH pde6c HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cone dystrophy Cone dystrophy 4 613093
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic retina morphogenesis in camera-type eye (more)
    Molecular Function 3',5'-cyclic-nucleotide phosphodiesterase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002073 (1)
  • InterPro:IPR003018 (1)
  • InterPro:IPR003607 (1)
  • InterPro:IPR023088 (1)
  • InterPro:IPR023174 (1)
  • InterPro:IPR029016 (1)
  • InterPro:IPR036971 (1)
  • PROSITE:PS00126 (1)
  • Pfam:PF00233 (1)
  • Pfam:PF01590 (1)
  • EC:3.1.4.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pde6c-001 (1) 4527
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-pde6c (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pde6c No data available
    MARKER RELATIONSHIPS
    pde6cContained in: [BAC] CH211-149K17 (1) (order this)
    pde6cEncodes: [EST] fm09c08 (1)
    [cDNA] MGC:73085 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200871 (1) 4544bp
    Genomic GenBank:AL929469 (1) 146415bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IG78 (1) 854aa
    Sequence Clusters UniGene:117127 (1)
    Sequence Information (all 13)
    OTHER pde6c GENE PAGES
  • Alliance (1)
  • Gene:393845 (1)
  • VEGA:OTTDARG00000020493 (1)
  • Ensembl(GRCz10):ENSDARG00000100397 (1)
  • ORTHOLOGY for pde6c (Chr: 12)
    CITATIONS (42)