Gene

rlbp1a

ID
ZDB-GENE-040426-1662
Name
retinaldehyde binding protein 1a
Symbol
rlbp1a Nomenclature History
Previous Names
  • cralbpb (1)
  • rlbp1b (1)
  • rlbp1l
  • zgc:73076
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol bisphosphate binding activity. Involved in optokinetic behavior. Is expressed in brain; optic vesicle; and visual system. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Orthologous to human RLBP1 (retinaldehyde binding protein 1).
Genome Resources
Note
None
Expression
All Expression Data
15 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rlbp1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Bothnia retinal dystrophy Alliance Bothnia retinal dystrophy 607475
fundus albipunctatus Alliance Fundus albipunctatus 136880
fundus albipunctatus Alliance Retinitis punctata albescens 136880
Newfoundland cone-rod dystrophy Alliance Newfoundland rod-cone dystrophy 607476
Associated With rlbp1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001251 CRAL-TRIO lipid binding domain
Domain IPR011074 CRAL/TRIO, N-terminal domain
Homologous_superfamily IPR036273 CRAL/TRIO, N-terminal domain superfamily
Homologous_superfamily IPR036865 CRAL-TRIO lipid binding domain superfamily
Domain Details Per Protein
Protein Length CRAL-TRIO lipid binding domain CRAL-TRIO lipid binding domain superfamily CRAL/TRIO, N-terminal domain CRAL/TRIO, N-terminal domain superfamily
UniProtKB:B0S6Y7 227
UniProtKB:F1QVD3 312
UniProtKB:Q6PC74 312
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-rlbp polyclonal Rabbit
  • IHC
  • WB
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations