Gene

gpr143

ID
ZDB-GENE-040426-1476
Name
G protein-coupled receptor 143
Symbol
gpr143 Nomenclature History
Previous Names
  • zgc:65915
  • zgc:77322 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have L-DOPA receptor activity; amino acid binding activity; and dopamine binding activity. Involved in melanosome organization. Predicted to localize to melanosome membrane and plasma membrane. Human ortholog(s) of this gene implicated in congenital nystagmus. Is expressed in neural crest; pigment cell; retina; and retinal pigmented epithelium. Orthologous to human GPR143 (G protein-coupled receptor 143).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Burgoyne et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gpr143 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital nystagmus 6 Alliance Nystagmus 6, congenital, X-linked 300814
ocular albinism 1 Alliance Ocular albinism, type I, Nettleship-Falls type 300500
Associated With gpr143 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:A0A8M3AWB8 412
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations