ZFIN ID: ZDB-GENE-040426-1469
Gene Name: one cut homeobox 1
Gene Symbol: onecut1    Nomenclature History

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Previous Names: onecut1l, hnf-6 (1), hnf6 (1), zgc:65904, zgc:77450

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have DNA binding activity. Involved in intrahepatic bile duct development. Predicted to localize to the nucleus. Is expressed in several structures, including digestive system; nervous system; presumptive neural retina; pronephric duct; and trigeminal placode. Orthologous to human ONECUT1 (one cut homeobox 1).
Genome Resources: Alliance (1),  Gene:393545 (1),  Ensembl(GRCz11):ENSDARG00000007982 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-onecut1 N/A 3
MO2-onecut1 N/A 1
DISEASE ASSOCIATED WITH onecut1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH onecut1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intrahepatic bile duct development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001356 Homeobox domain
Domain IPR003350 CUT domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA onecut1-201 (1)    Ensembl 1858
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM onecut1 No data available
MARKER RELATIONSHIPS
onecut1 Contained in: [BAC] CH211-215D8 (1)
onecut1 Encodes: [cDNA] MGC:65904 (1), MGC:77450 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200573 (1) 1860 nt
Genomic GenBank:BX908748 (1) 212425 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q5MD19 (1) 461 aa
Sequence Information (all 20)
ORTHOLOGY for onecut1 ( Chr: 18 )
CITATIONS (32)