Gene

spop

ID
ZDB-GENE-040426-1378
Name
speckle type BTB/POZ protein
Symbol
spop Nomenclature History
Previous Names
  • zgc:64140
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to localize to Cul3-RING ubiquitin ligase complex; cytoplasm; and nucleus. Orthologous to human SPOP (speckle type BTB/POZ protein).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Boysen et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spop Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nabais Sa-de Vries syndrome, type 1 618828
Nabais Sa-de Vries syndrome, type 2 618829
Associated With spop Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR002083 MATH/TRAF domain
Domain IPR034089 SPOP, C-terminal BACK domain
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain MATH/TRAF domain SKP1/BTB/POZ domain superfamily SPOP, C-terminal BACK domain TRAF-like
UniProtKB:A7YYH8 374
UniProtKB:Q7T330 374
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations