Gene

spop

ID
ZDB-GENE-040426-1378
Name
speckle type BTB/POZ protein
Symbol
spop Nomenclature History
Previous Names
  • zgc:64140
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to localize to Cul3-RING ubiquitin ligase complex; cytoplasm; and nucleus. Orthologous to human SPOP (speckle type BTB/POZ protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Boysen et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spop Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nabais Sa-de Vries syndrome, type 1 618828
Nabais Sa-de Vries syndrome, type 2 618829
Associated With spop Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR002083 MATH/TRAF domain
Domain IPR034089 SPOP, C-terminal BACK domain
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain MATH/TRAF domain SKP1/BTB/POZ domain superfamily SPOP, C-terminal BACK domain TRAF-like
UniProtKB:A7YYH8 374
UniProtKB:Q7T330 374
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations