ZFIN ID: ZDB-GENE-040426-1315
Gene Name: hypoxia inducible factor 1 subunit alpha, like
Gene Symbol: hif1al    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: hif-3 (1), Hif3a (1), zgc:63965

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Exhibits beta-catenin binding activity and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including neuron apoptotic process; response to activity; and response to hypoxia. Localizes to beta-catenin-TCF complex. Is expressed in several structures, including digestive system; head; heart; inner ear; and pleuroperitoneal region. Orthologous to human HIF3A (hypoxia inducible factor 3 subunit alpha).
Genome Resources: Alliance (1),  Gene:393376 (1),  Ensembl(GRCz11):ENSDARG00000100826 (1)
GENE EXPRESSION
All Expression Data: 11 figures from 9 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63965]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb20180620 Small Deletion Unknown Unknown CRISPR
ihb20180621 Insertion Unknown Unknown CRISPR
mi600 Small Deletion Exon 11 Unknown CRISPR
mi601 Small Deletion Unknown Unknown CRISPR
sa18426 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45539 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hif1al 1
    CRISPR2-hif1al 1
    CRISPR3-hif1al 1
    MO1-hif1al N/A 4
    MO2-hif1al N/A 1
    MO3-hif1al N/A 1
    DISEASE ASSOCIATED WITH hif1al HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hif1al VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component beta-catenin-TCF complex (more)
    Molecular Function beta-catenin binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hif1al-201 (1)    Ensembl 900
    hif1al-203 (1)    Ensembl 3185
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-hif1al polyclonal Rabbit WB 3
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hif1al No data available
    MARKER RELATIONSHIPS
    hif1al Contained in: [BAC] CH211-169I9 (1), DKEY-54N8 (1) (order this)
    hif1al Encodes: [cDNA] MGC:63965 (1), MGC:174046 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200405 (1) 3197 nt
    Genomic GenBank:CU856359 (1) 216188 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IBR4 (1) 626 aa
    Sequence Information (all 38)
    ORTHOLOGY for hif1al ( Chr: 15 )
    CITATIONS (43)