ZFIN ID: ZDB-GENE-040426-1121
Gene Name: UF2 component of NDC80 kinetochore complex
Gene Symbol: nuf2    Nomenclature History

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Previous Names: un-named hi2769, unm hi2769, zgc:56708

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Involved in heart development. Predicted to localize to the Ndc80 complex and condensed nuclear chromosome kinetochore. Is expressed in proliferative region. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex).
Genome Resources: Alliance (1),  Gene:393280 (1),  Ensembl(GRCz11):ENSDARG00000034624 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [MGC:56708]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE
Data: 3 figures from 3 publications
Observed in:
DISEASE ASSOCIATED WITH nuf2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH nuf2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process heart development (more)
Cellular Component Ndc80 complex (more)
Molecular Function protein-containing complex binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR005549 Kinetochore protein Nuf2
Homologous_superfamily IPR038275 Nuf2, N-terminal domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA nuf2-201 (1)    Ensembl 1567
nuf2-202 (1)    Ensembl 542
nuf2-203 (1)    Ensembl 914
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM nuf2 No data available
MARKER RELATIONSHIPS
nuf2 Contained in: [BAC] CH211-159E12 (1)
nuf2 Encodes: [cDNA] MGC:56708 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_200310 (1) 1640 bp
Genomic GenBank:CR855375 (1) 178231 bp
Select Tool
Polypeptide UniProtKB:Q7ZW63 (1) 454 aa
Sequence Information (all 13)
ORTHOLOGY for nuf2 ( Chr: 11 )
CITATIONS (29)