ZFIN ID: ZDB-GENE-030909-7
Gene Name: retinol dehydrogenase 10b
Gene Symbol: rdh10b    Nomenclature History

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Previous Names: rdh10 (1), cb804 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in oxidation-reduction process; retinoic acid biosynthetic process; and retinol metabolic process. Predicted to localize to lipid droplet. Is expressed in several structures, including axis; notochord; pleuroperitoneal region; tail bud; and yolk syncytial layer. Orthologous to human RDH10 (retinol dehydrogenase 10).
Genome Resources: Alliance (1),  Gene:378722 (1),  Ensembl(GRCz11):ENSDARG00000012369 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 5 publications
Directly Submitted Expression Data: 3 figures (4 images) from Thisse et al., 2001 [cb804]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa25824 Point Mutation Unknown Premature Stop ENU
sa38337 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rdh10b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rdh10b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function NADP-retinol dehydrogenase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rdh10b-201 (1)    Ensembl 1785
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rdh10b No data available
    MARKER RELATIONSHIPS
    rdh10b Contained in: [BAC] CH211-193N21 (1)
    rdh10b Encodes: [EST] cb804 (1) (order this)
    [cDNA] MGC:64016 (1), MGC:191545 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201331 (1) 1571 nt
    Genomic GenBank:CT027743 (1) 101895 nt
    Select Tool
    Polypeptide UniProtKB:B2GPJ5 (1) 336 aa
    Sequence Information (all 18)
    ORTHOLOGY for rdh10b ( Chr: 2 )
    CITATIONS (36)