Gene

itgb1b

ID
ZDB-GENE-030909-10
Name
integrin, beta 1b
Symbol
itgb1b Nomenclature History
Previous Names
  • cb810 (1)
  • cr3 (1)
  • itgb1
  • beta1-2 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity. Involved in several processes, including Kupffer's vesicle development; cell migration involved in gastrulation; and striated muscle cell development. Predicted to localize to integrin complex. Is expressed in several structures, including cardiovascular system; digestive system; mesoderm; muscle; and pleuroperitoneal region. Orthologous to human ITGB1 (integrin subunit beta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
24 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
24 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itgb1b Human Ortholog
No data available
Associated With itgb1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002369 Integrin beta subunit, VWA domain
Domain IPR012896 Integrin beta subunit, tail
Domain IPR013111 EGF-like domain, extracellular
Domain IPR014836 Integrin beta subunit, cytoplasmic domain
Domain IPR016201 PSI domain
Domain IPR033760 Integrin beta N-terminal
Domain IPR040622 Integrin beta, epidermal growth factor-like domain 1
Family IPR015812 Integrin beta subunit
Homologous_superfamily IPR032695 Integrin domain superfamily
Homologous_superfamily IPR036349 Integrin beta tail domain superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain, extracellular Integrin beta, epidermal growth factor-like domain 1 Integrin beta N-terminal Integrin beta subunit Integrin beta subunit, cytoplasmic domain Integrin beta subunit, tail Integrin beta subunit, VWA domain Integrin beta tail domain superfamily Integrin domain superfamily PSI domain von Willebrand factor A-like domain superfamily
UniProtKB:A0A0R4IR57 516
UniProtKB:Q3YAA0 795
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA itgb1b-201 (1) Ensembl 1,563 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-itgb1b polyclonal
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations