ZFIN ID: ZDB-GENE-030902-4 |
Gene Name: | adenosine deaminase 2a | ||||||
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Gene Symbol: | ada2a Nomenclature History | ||||||
Previous Names: | ADA2-1 (1), cecr1, cecr1a, fj65e02, wu:fj65e02 (1) | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 25 Mapping Details/Browsers | ||||||
Description: | Predicted to have several functions, including adenosine deaminase activity; signaling receptor binding activity; and zinc ion binding activity. Predicted to be involved in adenosine catabolic process and inosine biosynthetic process. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in Sneddon syndrome. Is expressed in several structures, including cardiovascular system; gill; kidney; liver; and notochord. Orthologous to human ADA2 (adenosine deaminase 2). | ||||||
Genome Resources: | Alliance (1), Gene:373884 (1), Ensembl(GRCz11):ENSDARG00000051746 (2) |
All Expression Data: | 6 figures from 6 publications |
Directly Submitted Expression Data: | 1 figure (1 image) from Thisse et al., 2004 [MGC:55247] |
Wild-type Stages, Structures: | Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult) |
Curated Microarray Expression: | GEO (1) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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la023164Tg | Transgenic Insertion | Unknown | Unknown | DNA |
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sa38038 | Point Mutation | Unknown | Splice Site | ENU |
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sa44262 | Point Mutation | Unknown | Premature Stop | ENU |
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Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
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Sneddon syndrome | Alliance | ?Sneddon syndrome | 182410 |
Vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome | 615688 |
Ontology | GO Term |
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Biological Process | adenosine catabolic process (more) |
Cellular Component | extracellular space (more) |
Molecular Function | adenosine deaminase activity (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
ada2a-201
(1)
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2484 |
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Browsers: UCSC, NCBI, Ensembl, ZFIN |
ada2a Contained in: | [BAC] CH211-276C7 (1) (order this) |
ada2a Encodes: |
[EST]
fj65e02 (1)
[cDNA] MGC:55247 (1) (order this) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_001033717 (1) | 2505 bp |
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Genomic | GenBank:BX004976 (1) | 151137 bp | |
Polypeptide | UniProtKB:F1R9S0 (1) | 503 aa |
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Sequence Clusters | UniGene:77275 (1) |