Gene
birc5b
- ID
- ZDB-GENE-030826-2
- Name
- baculoviral IAP repeat containing 5b
- Symbol
- birc5b Nomenclature History
- Previous Names
-
- survivin 2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in several processes, including circulatory system development; nuclear division; and regulation of apoptotic process. Predicted to localize to cytoplasm; nucleus; and spindle microtubule. Is expressed in several structures, including axial blood vessel; caudal vein plexus; intermediate cell mass of mesoderm; nervous system; and unfertilized egg. Human ortholog(s) of this gene implicated in prostate cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5) and BIRC7 (baculoviral IAP repeat containing 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Repeat | IPR001370 | BIR repeat |
Domain Details Per Protein
Protein | Length | BIR repeat |
---|---|---|
UniProtKB:Q90WU8
|
128 | |
UniProtKB:A0A8M9PSV1
|
102 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
birc5b-201
(1)
|
Havana | 598 nt | |
ncRNA |
birc5b-002
(1)
|
Havana | 612 nt | |
ncRNA |
birc5b-003
(1)
|
Havana | 525 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab2-birc5 | monoclonal | IgG | Rabbit |
|
Cell Signaling Technology, Inc.
|
3 |
Plasmids
No data available