Gene

bcl2l10

ID
ZDB-GENE-030825-2
Name
BCL2 like 10
Symbol
bcl2l10 Nomenclature History
Previous Names
  • mcl1l (1)
  • Boo/DIVA
  • NR-13 (1)
  • nrz (1)
  • sb:cb78
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including epiboly; regulation of release of sequestered calcium ion into cytosol; and somitogenesis. Localizes to mitochondrion. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10).
Genome Resources
Note
None
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bcl2l10 Human Ortholog
No data available
Associated With bcl2l10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020726 Apoptosis regulator, Bcl-2, BH2 motif, conserved site
Family IPR002475 Bcl2-like
Family IPR026298 Blc2 family
Homologous_superfamily IPR036834 Blc2-like superfamily
Domain Details Per Protein
Protein Length Apoptosis regulator, Bcl-2, BH2 motif, conserved site Bcl2-like Blc2 family Blc2-like superfamily
UniProtKB:Q8UWD5 176
UniProtKB:Q568W6 203
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bcl2l10 polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations