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ZIRC
ZFIN ID: ZDB-GENE-030825-2
Gene Name: BCL2 like 10
Gene Symbol: bcl2l10    Nomenclature History

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Previous Names: mcl1l (1), Boo/DIVA, NR-13 (1), nrz (1), sb:cb78

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including epiboly; regulation of release of sequestered calcium ion into cytosol; and somitogenesis. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Orthologous to several human genes including BCL2L10 (BCL2 like 10).
Genome Resources: Alliance (1),  Gene:373113 (1),  Ensembl(GRCz11):ENSDARG00000026766 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23356 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23357 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36704 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bcl2l10 N/A 4
    DISEASE ASSOCIATED WITH bcl2l10 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bcl2l10 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of apoptotic process (more)
    Cellular Component mitochondrion (more)
    Molecular Function protein binding (more)
    GO Terms (all 17)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bcl2l10-201 (1)    Ensembl 1349
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-bcl2l10 polyclonal Rabbit IHC, WB 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bcl2l10 No data available
    MARKER RELATIONSHIPS
    bcl2l10 Contained in: [BAC] CH211-235F12 (1) (order this)
    bcl2l10 Encodes: [EST] cb78 (1) (order this)
    [cDNA] MGC:123143 (1) (order this)
    bcl2l10 Has Artifact: [EST] fb96a11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194398 (1) 1378 bp
    Genomic GenBank:AL935189 (1) 170193 bp
    Select Tool
    Polypeptide UniProtKB:Q568W6 (1) 203 aa
    Sequence Clusters UniGene:78077 (1)
    Sequence Information (all 17)
    ORTHOLOGY for bcl2l10 ( Chr: 18 )
    CITATIONS (39)