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ZIRC
ZFIN ID: ZDB-GENE-030819-1
Gene Name: tumor protein p63
Gene Symbol: tp63
Sequence Ontology ID : SO:0001217

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Previous Names: p63 (1), delta-Np63 (1), fc89f04, id:ibd3516 (1), tp73l (1), wu:fc89f04, wu:fk85h07, wu:fk88b02 (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits DNA binding activity. Involved in several processes, including epidermis morphogenesis; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and negative  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2525 Point Mutation Unknown Missense ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015877Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025475Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029208Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029209Tg Transgenic Insertion Unknown Unknown DNA
    sa12599 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15970 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33878 Point Mutation Unknown Missense, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH tp63 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ADULT syndrome ADULT syndrome 103285
    ankyloblepharon-ectodermal defects-cleft lip/palate syndrome Hay-Wells syndrome 106260
    ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3 Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 604292
    orofacial cleft 8 Orofacial cleft 8 618149
    Rapp-Hodgkin syndrome Rapp-Hodgkin syndrome 129400
    split hand-foot malformation 4 Split-hand/foot malformation 4 605289
    Limb-mammary syndrome 603543
    DISEASE ASSOCIATED WITH tp63 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tp63-201 (1) 2783
    tp63-202 (1) 2959
    tp63-203 (1) 1444
    tp63-204 (1) 2497
    tp63-205 (1) 1731
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    MARKER RELATIONSHIPS
    tp63 Contained in: [BAC] CH211-240D20 (order this), DKEY-11H2 (1) (order this), DKEY-13D19 (1) (order this)
    tp63 Encodes: [EST] eu912 (1), fc89f04, fk85h07 (1), fk88b02 (1), ibd3516 (1) (order this)
    [cDNA] MGC:92012 (1) (order this), MGC:174146 (1) (order this), MGC:192897 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_152986 (1) 3004 bp
    Genomic GenBank:BX004878 (1) 254657 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E9QG65 (1) 632 aa
    Sequence Clusters UniGene:32588 (1)
    Sequence Information (all 55)
    ORTHOLOGY for tp63 ( Chr: 6 )
    CITATIONS (97)