Gene

glo1

ID
ZDB-GENE-030722-9
Name
glyoxalase 1
Symbol
glo1 Nomenclature History
Previous Names
  • cb554 (1)
  • wu:fb82g09
  • zgc:66035
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Enables lactoylglutathione lyase activity. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in autistic disorder; diabetic retinopathy; end stage renal disease; type 2 diabetes mellitus; and vascular disease. Orthologous to human GLO1 (glyoxalase I).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With glo1 Human Ortholog
No data available
Associated With glo1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018146 Glyoxalase I, conserved site
Domain IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain
Domain IPR037523 Vicinal oxygen chelate (VOC) domain
Family IPR004361 Glyoxalase I
Homologous_superfamily IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Domain Details Per Protein
Protein Length Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/fosfomycin resistance/dioxygenase domain Glyoxalase I Glyoxalase I, conserved site Vicinal oxygen chelate (VOC) domain
UniProtKB:Q6P696 180
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-glo1 monoclonal IgG2b Rat
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations