ZFIN ID: ZDB-GENE-030711-4
Gene Name: ATPase H+ transporting V1 subunit B2
Gene Symbol: atp6v1b2    Nomenclature History

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Previous Names: atp6v1bb, vatB2 (1), fj51e01, wu:fj51e01 (1), zgc:109771

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have ATP binding activity. Predicted to be involved in ATP metabolic process and proton transmembrane transport. Predicted to localize to proton-transporting V-type ATPase, V1 domain. Orthologous to human ATP6V1B2 (ATPase H+ transporting V1 subunit B2).
Genome Resources: Alliance (1),  Gene:359840 (1),  Ensembl(GRCz11):ENSDARG00000043465 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15671 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41634 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-atp6v1b2 N/A 1
    DISEASE ASSOCIATED WITH atp6v1b2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant congenital deafness with onychodystrophy Alliance Deafness, congenital, with onychodystrophy, autosomal dominant 124480
    Zimmermann-Laband syndrome 2 616455
    DISEASE ASSOCIATED WITH atp6v1b2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ATP metabolic process (more)
    Cellular Component proton-transporting V-type ATPase, V1 domain (more)
    Molecular Function ATP binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-atp6v1b2 Rabbit IHC 3
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp6v1b2 No data available
    MARKER RELATIONSHIPS
    atp6v1b2 Encodes: [EST] fj51e01 (1)
    [cDNA] MGC:109771 (1), MGC:136655 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_182879 (1) 2407 nt
    Polypeptide UniProtKB:A4FUM8 (1) 509 aa
    Sequence Information (all 19)
    ORTHOLOGY for atp6v1b2 ( Chr: 10 )
    CITATIONS (24)