ZFIN ID: ZDB-GENE-030616-554
Gene Name: solute carrier family 17 member 6b
Gene Symbol: slc17a6b    Nomenclature History

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Previous Names: slc17a6, blu, blumenkohl, si:packt73.2, si:packt90.2, si:xx-packt73.2 (1), VGLUT2.1 (2), vglut2a (2)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have L-glutamate transmembrane transporter activity. Involved in chemical synaptic transmission and visual perception. Predicted to localize to excitatory synapse and integral component of synaptic vesicle membrane. Is expressed in nervous system and trigeminal placode. Orthologous to human SLC17A6 (solute carrier family 17 member 6).
Genome Resources: Alliance (1),  Gene:100149756 (1),  Ensembl(GRCz11):ENSDARG00000041150 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016081Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15613 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31579 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tc257z Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-slc17a6b
    1
    CRISPR2-slc17a6b 2
    MO1-slc17a6b N/A 1
    DISEASE ASSOCIATED WITH slc17a6b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc17a6b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chemical synaptic transmission (more)
    Cellular Component cell junction (more)
    Molecular Function symporter activity (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc17a6b-202 (1)    Ensembl 5680
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-slc17a6 polyclonal Rabbit IHC, WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc17a6b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(slc17a6b:DsRed) slc17a6b DsRed Danio rerio 1 17
    Tg(slc17a6b:EGFP) slc17a6b EGFP Danio rerio 1 17
    TgBAC(slc17a6b:GAL4FF) slc17a6b GAL4FF Danio rerio 1 8
    TgBAC(slc17a6b:LOXP-DsRed-LOXP-GFP) slc17a6b DsRedGFP Danio rerio 1 37
    TgBAC(slc17ab:LOXP-mCherry-LOXP-GAL4FF) slc17a6b GAL4FFmCherry Danio rerio 1 5
    MARKER RELATIONSHIPS
    slc17a6b Contained in: [BAC] CH211-150G13 (1), DKEY-46P12 (1) (order this)
    [PAC] XX-PACKT73, XX-PACKT90
    slc17a6b Encodes: [EST] eu1082 (1)
    [cDNA] MGC:193644 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128821 (1) 1887 nt
    Genomic GenBank:AL929252 (1) 173244 nt
    Select Tool
    Polypeptide UniProtKB:Q5W8I8 (1) 584 aa
    Sequence Information (all 27)
    ORTHOLOGY for slc17a6b ( Chr: 7 )
    CITATIONS (90)