Gene

abcc4

ID
ZDB-GENE-030616-511
Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Symbol
abcc4 Nomenclature History
Previous Names
  • cb1019 (1)
  • leakytail (1)
  • lkt (1)
  • sb:eu668
  • sb:eu872
  • si:busm1-52i16.4
  • si:dz202l16.5
  • si:dz52i16.4
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Exhibits efflux transmembrane transporter activity. Involved in detoxification and regulation of cilium assembly. Localizes to plasma membrane. Is expressed in several structures, including Kupffer's vesicle; digestive system; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Jin et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abcc4 Human Ortholog
No data available
Associated With abcc4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Domain IPR011527 ABC transporter type 1, transmembrane domain
Family IPR009147 Cystic fibrosis transmembrane conductance regulator
Family IPR030240 Multidrug resistance-associated protein 4
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036640 ABC transporter type 1, transmembrane domain superfamily
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC transporter, conserved site ABC transporter-like ABC transporter type 1, transmembrane domain ABC transporter type 1, transmembrane domain superfamily Cystic fibrosis transmembrane conductance regulator Multidrug resistance-associated protein 4 P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A2R8Q6E0 1327
UniProtKB:Q7T022 61
UniProtKB:Q8QFL6 1327
UniProtKB:F1QIK5 1327
UniProtKB:B2LUM7 1327
UniProtKB:M1FT22 1327
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations