ZFIN ID: ZDB-GENE-030616-360
Gene Name: MAM domain containing glycosylphosphatidylinositol anchor 2a
Gene Symbol: mdga2a    Nomenclature History

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Previous Names: mamdc1, si:dz209d10.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Involved in facial nerve formation; regulation of motor neuron migration; and trigeminal motor nucleus development. Predicted to localize to membrane. Is expressed in several structures, including brainstem; cranial nerve; muscle; pharyngeal musculature; and posterior lateral line. Orthologous to human MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2).
Genome Resources: Alliance (1),  Gene:368826 (1),  Ensembl(GRCz11):ENSDARG00000024017 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020051Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9344 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28871 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mdga2a N/A 1
    MO2-mdga2a N/A 1
    MO3-mdga2a N/A 1
    DISEASE ASSOCIATED WITH mdga2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mdga2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process facial nerve formation (more)
    Cellular Component membrane (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mdga2a-201 (1)    Ensembl 4138
    mdga2a-202 (1)    Ensembl 585
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-mdga2a polyclonal Rabbit IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mdga2a No data available
    MARKER RELATIONSHIPS
    mdga2a Contained in: [BAC] CH211-266M11 (1), DKEY-11J8 (1) (order this)
    [PAC] BUSM1-209D10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009293141 (1)
    Genomic GenBank:BX465838 (1) 229940 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1RDD1 (1) 957 aa
    Sequence Information (all 25)
    ORTHOLOGY for mdga2a ( Chr: 17 )
    CITATIONS (19)