Gene

ccdc65

ID
ZDB-GENE-030616-358
Name
coiled-coil domain containing 65
Symbol
ccdc65 Nomenclature History
Previous Names
  • si:busm1-202l16.3 (1)
  • si:dz202l16.3
  • zgc:92302
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Involved in axonemal dynein complex assembly and cilium-dependent cell motility. Acts upstream of or within regulation of cilium movement. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be part of axonemal dynein complex. Is expressed in pronephric duct and spinal cord. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 27. Orthologous to human CCDC65 (coiled-coil domain containing 65).
Genome Resources
Note
novel protein similar to human NYD-SP28
Comparative Information
Expression
All Expression Data
1 figure from Austin-Tse et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Austin-Tse et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccdc65 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 27 Alliance Ciliary dyskinesia, primary, 27 615504
Associated With ccdc65 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR039505 Dynein regulatory complex protein 1/2, N-terminal
Family IPR039750 Dynein regulatory complex protein
Domain Details Per Protein
Protein Length Dynein regulatory complex protein Dynein regulatory complex protein 1/2, N-terminal
UniProtKB:Q6DHI2 492
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations