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ZIRC
ZFIN ID: ZDB-GENE-030616-358
Gene Name: coiled-coil domain containing 65
Gene Symbol: ccdc65
Sequence Ontology ID : SO:0000704

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Previous Names: si:busm1-202l16.3 (1), si:dz202l16.3, zgc:92302

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
Note: novel protein similar to human NYD-SP28
AUTOMATED DESCRIPTION
Involved in regulation of cilium movement; predicted to localize to the axoneme; orthologous to human CCDC65 (coiled-coil domain containing 65).
GENE EXPRESSION
All Expression Data: Fig. 1 from Austin-Tse et al., 2013
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6066 Point Mutation Unknown Premature Stop ENU
sa20626 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH ccdc65 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    primary ciliary dyskinesia 27 Ciliary dyskinesia, primary, 27 615504
    DISEASE ASSOCIATED WITH ccdc65 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cilium movement (more)
    Cellular Component axonemal dynein complex (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR039505 (1)
  • InterPro:IPR039750 (1)
  • Pfam:PF14772 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ccdc65-201 (1) 1531
    ottdart00000001492 (1) 1344
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ccdc65 No data available
    MARKER RELATIONSHIPS
    ccdc65Contained in: [BAC] CH211-241A17 (1) (order this)
    [PAC] BUSM1-202L16 (1) (order this)
    ccdc65Encodes: [cDNA] MGC:92302 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002603 (1) 1571bp
    Genomic GenBank:AL953886 (1) 154152bp
    Select Tool
    Polypeptide UniProtKB:Q6DHI2 (1) 492aa
    Sequence Clusters UniGene:133171 (1)
    Sequence Information (all 17)
    ORTHOLOGY for ccdc65 (Chr: 6)
    CITATIONS (21)