ZFIN ID: ZDB-GENE-030516-3
Gene Name: collagen type XVIII, alpha 1
Gene Symbol: col18a1
Previous Names: cb371 (1), cb529 (1), fc96d06, sb:cb529 (1), wu:fb47h10, wu:fb77g12, wu:fc50f04, wu:fc96d06, wu:fk02h12
Location: Chr: 9   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 23 figures from 6 publications
Directly Submitted Expression Data: 5 figures (20 images) from Thisse et al., 2001 [cb529]
  8 figures (13 images) from Rauch et al., 2003 [fc50f04]
  6 figures (21 images) from Thisse et al., 2001 [cb371]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  adaxial cell, alar plate midbrain region, aortic arch, blood vessel (all 46) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la026994Tg, la026995Tg, la026996Tg, la029609Tg, la029610Tg
Knockdown reagents: MO1-col18a1 (1), MO2-col18a1 (1)
PHENOTYPE
Data: Fig. 4 from Banerjee et al., 2013
Observed in: neural crest cell migration

Phenotype of Human Orthologue OMIM Phenotype ID
Knobloch syndrome, type 1 267750
GENE ONTOLOGY
Ontology GO Term
Biological Process neural crest cell migration (more)
Cellular Component collagen trimer (more)
Molecular Function structural molecule activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001791 (1)
  • InterPro:IPR008160 (1)
  • InterPro:IPR010515 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR016186 (1)
  • InterPro:IPR016187 (1)
  • InterPro:IPR020067 (1)
  • InterPro:IPR026917 (1)
  • PROSITE:PS50038 (1)
  • Pfam:PF01391 (1)
  • Pfam:PF01392 (1)
  • Pfam:PF06482 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col18a1-001 (1) 6365
    col18a1-002 (1) 5515
    col18a1-003 (1) 5579
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col18a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    col18a1 Contained in: [BAC] DKEY-237E16 (1), DKEYP-30E7 (1)
    col18a1 Encodes: [EST] cb371 (1) (order this), cb529 (2) (order this), fb47h10 (1), fb77g12 (1), fc50f04 (1), fc96d06, fk02h12
    [cDNA] MGC:195107 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039630 (1) 4191 bp
    Genomic GenBank:BX927363 (1) 134994 bp
    Select Tool
    Polypeptide UniProtKB:B0S8G4 (1) 1645 aa
    Sequence Clusters UniGene:52833 (1)
    Sequence Information (all 42)
    OTHER col18a1 GENE PAGES
  • Gene:564123 (1)
  • VEGA:OTTDARG00000022631 (1)
  • Ensembl(Zv9):ENSDARG00000036558 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish col18a1 9  
    Human COL18A1 21 (21q22.3)
  • OMIM:120328
  • Gene:80781
  • Mouse Col18a1 10 ( 39.72 cM)
  • MGI:88451
  • Gene:12822
  • Orthology Details
    CITATIONS (29)