ZFIN ID: ZDB-GENE-030516-3
Gene Name: collagen type XVIII, alpha 1
Gene Symbol: col18a1
Previous Names: cb371 (1), cb529 (1), fc96d06, sb:cb529 (1), wu:fb47h10, wu:fb77g12, wu:fc50f04, wu:fc96d06, wu:fk02h12
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 7 publications
Directly Submitted Expression Data: 5 figures (20 images) from Thisse et al., 2001 [cb529]
  8 figures (13 images) from Rauch et al., 2003 [fc50f04]
  6 figures (21 images) from Thisse et al., 2001 [cb371]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  adaxial cell, alar plate midbrain region, aortic arch, blood vessel (all 47) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la026994Tg Transgenic Insertion DNA
la026995Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026996Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029609Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029610Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-col18a1 (1), MO2-col18a1 (1)
    PHENOTYPE
    Data: Fig. 4 from Banerjee et al., 2013
    Observed in: neural crest cell migration
    DISEASE ASSOCIATED WITH col18a1 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Knobloch syndrome, type 1 267750
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process neural crest cell migration (more)
    Cellular Component collagen trimer (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001791 (1)
  • InterPro:IPR008160 (1)
  • InterPro:IPR010515 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR016186 (1)
  • InterPro:IPR016187 (1)
  • InterPro:IPR020067 (1)
  • PROSITE:PS50038 (1)
  • Pfam:PF01391 (1)
  • Pfam:PF01392 (1)
  • Pfam:PF06482 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA col18a1-001 (1) 6365
    col18a1-002 (1) 5515
    col18a1-003 (1) 5579
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col18a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    col18a1Contained in: [BAC] DKEY-237E16 (1) (order this), DKEYP-30E7 (1)
    col18a1Encodes: [EST] cb371 (1) (order this), cb529 (2) (order this), fb47h10 (1), fb77g12 (1), fc50f04 (1) (order this), fc96d06, fk02h12
    [cDNA] MGC:195107 (1)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039630 (1) 4191bp
    Genomic GenBank:BX927363 (1) 134994bp
    Select Tool
    Polypeptide UniProtKB:B0S8G4 (1) 1645aa
    Sequence Clusters UniGene:52833 (1)
    Sequence Information (all 41)
    OTHER col18a1 GENE PAGES 
  • Gene:564123 (1)
  • VEGA:OTTDARG00000022631 (1)
  • Ensembl(GRCz10):ENSDARG00000036558 (1)
  • ORTHOLOGY for col18a1 (Chr: 9) 
    Species Symbol Chromosome Accession # Evidence
    Human COL18A1 21
  • Gene:80781
  • OMIM:120328
  • HGNC:2195
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Col18a1 10
  • MGI:88451
  • Gene:12822
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (31)