ZFIN ID: ZDB-GENE-030508-1
Gene Name: orthodenticle homolog 5
Gene Symbol: otx5
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: cb828 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity; involved in circadian regulation of gene expression and positive regulation of transcription, DNA-templated; predicted to localize to the nucleus;  ...
GENE EXPRESSION
All Expression Data: 75 figures from 48 publications
Directly Submitted Expression Data: 5 figures (16 images) from Thisse et al., 2001 [cb828]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 5 figures from 4 publications
Observed in:
DISEASE ASSOCIATED WITH otx5 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
cone-rod dystrophy 2 Cone-rod retinal dystrophy-2 120970
Leber congenital amaurosis 7 Leber congenital amaurosis 7 613829
DISEASE ASSOCIATED WITH otx5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003025 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR013851 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03529 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA otx5-201 (1) 1747
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM otx5 No data available
    MARKER RELATIONSHIPS
    otx5Contained in: [Fosmid] CH1073-111C8 (1) (order this)
    otx5Encodes: [EST] cb828 (1) (order this)
    [cDNA] MGC:65752 (1) (order this), MGC:76843 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181331 (1) 1877bp
    Genomic GenBank:CU633848 (1) 35813bp
    Select Tool
    Polypeptide UniProtKB:F1R982 (1) 289aa
    Sequence Clusters UniGene:15426 (1)
    Sequence Information (all 17)
    OTHER otx5 GENE PAGES
  • Alliance (1)
  • Gene:353179 (1)
  • VEGA:OTTDARG00000035873 (1)
  • Ensembl(GRCz11):ENSDARG00000043483 (2)
  • ORTHOLOGY for otx5 (Chr: 15)
    CITATIONS (81)