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Gene

txnrd3

ID
ZDB-GENE-030327-3
Name
thioredoxin reductase 3
Symbol
txnrd3 Nomenclature History
Previous Names
  • TrxR1 (1)
  • TrxR2 (1)
  • txnrd1
  • cb682 (1)
  • cb683 (1)
  • fb83a08
  • wu:fb83a08 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable thioredoxin-disulfide reductase activity. Predicted to be involved in cell redox homeostasis. Predicted to be active in mitochondrion. Is expressed in several structures, including digestive system; hematopoietic system; nervous system; pectoral fin musculature; and ventral mesoderm. Orthologous to human TXNRD3 (thioredoxin reductase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With txnrd3 Human Ortholog
No data available
Associated With txnrd3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR011767 Glutaredoxin active site
Active_site IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site
Domain IPR002109 Glutaredoxin
Domain IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
Domain IPR011899 Glutaredoxin, eukaryotic/virial
Domain IPR023753 FAD/NAD(P)-binding domain
Family IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I
Family IPR006338 Thioredoxin/glutathione reductase selenoprotein
Homologous_superfamily IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily
Homologous_superfamily IPR036188 FAD/NAD(P)-binding domain superfamily
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length FAD/NAD-linked reductase, dimerisation domain superfamily FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain superfamily Glutaredoxin Glutaredoxin active site Glutaredoxin, eukaryotic/virial Pyridine nucleotide-disulphide oxidoreductase, class I Pyridine nucleotide-disulphide oxidoreductase, class I, active site Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Thioredoxin/glutathione reductase selenoprotein Thioredoxin-like superfamily
UniProtKB:A0A0R4IPH8 602
UniProtKB:Q802F7 288
UniProtKB:Q800Q8 193
UniProtKB:Q7T2C8 600
UniProtKB:A8WGN7 602
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations